Dr. Poongavanam Vasanthanathan

Post-Doctoral Research Fellow

Pharmacoinformatics Research Group, Department of Medicinal Chemistry, The Faculty of Life Sciences, University of Vienna Althanstrasse 14, 1090 Vienna, Austria.
E-mail: nathan.poongavanam@univie.ac.at / nobelvasanth@gmail.com

Current Project:

eTOX-Project:Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities-Fundad Innovative Medicines Initiative (IMI)

Research Interest

Actively involved in the early prediction drug ADMET properties especially metabolism (e.g., Cytochrome P450 and Transporter mediated) and toxicity which play a vital role in the metabolic clearance of more than 10% of currently marketed drugs and leads to considerable amount of drug attrition. In these purposes, various drug design and development computational methods have been applied such as QSARs, docking, virtual screening, pharmacophore modeling, molecular dynamic simulation, machine learning methods, design of experiments using D-Optimal onion design, partial least square, orthogonal PLS-discriminant analysis and binary QSAR studies.

Previous Research Places

Bio-structural Research, Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.(2007-2010)

Computational Medicinal Chemistry and Toxicology, Section of Molecular Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit, Amsterdam, The Netherlands. (2007-2010)